What is the effect of CBG? Explain the difference and effects with CBD!

Many people may be wondering, "What is CBG?"

Although there are people who know CBD, I think that many people are not familiar with the word CBG.

Therefore, in this article, we will explain in detail the effects of CBG, the differences from CBD, and the advantages and disadvantages.

This article will give you a comprehensive overview of CBG.

Summary of this article

CBG has almost no known toxicity or side effects.
Only products approved by the Ministry of Health, Labor and Welfare are sold in Japan.
CBG has few experimental events in humans and insufficient evidence for safety and efficacy
CBG is expected in various fields

What is CBD

CBD (cannabidiol) is a cannabinoid found in plants such as cannabis .

Since it does not contain the narcotic components of cannabis, it is licensed by the Ministry of Health, Labor and Welfare and is legally sold nationwide.

The reason why it is legal is that CBD falls under “mature stems of cannabis grass and its products, and cannabis seeds and their products” permitted by Article 1 of the Cannabis Control Law.

Reference: Cannabis Control Law (Law No. 124, July 10, 1948) - Ministry of Health, Labor and Welfare

https://www.mhlw.go.jp/web/t_doc?dataId=81108000&dataType=0&pageNo=1

Its application to stress, insomnia, anti-inflammatory effects, etc. is being researched, and it is an ingredient that is attracting attention from the medical and beauty industries .

What is CBG? Explain the safety of CBG!

When you hear CBG, you worry about whether it is safe to use, just like CBD.

However, CBG is the same cannabinoid as CBD and is considered non-addictive and non-psychoactive.

So here, we will explain in detail the ingredients and safety of CBG.

CBG is the mother of cannabinoids

CBG (cannabigerol), like CBD, is a cannabinoid .

CBG is said to be the mother of cannabinoids because it is produced by decarboxylation of cannabigerophyllic acid (CBG-A), an acidic component that is the base of cannabinoids.

It is an ingredient that is being studied for its application to diseases such as inhibition of intestinal inflammatory diseases, suppression of tumor growth, and antidepressant.

CBG is a legal product sold in Japan

CBG is a non-psychoactive cannabinoid, so it won't get you high .

It is expected to support the work of the ECS (entocannabinoid system), which is related to all bodily functions such as appetite, immune function, and nervous system.

CBG is attracting attention in various markets.

Almost no side effects have been confirmed, and the products approved by the Ministry of Health, Labor and Welfare are also sold in Japan, and can be purchased at e-commerce, organic specialty stores, beauty salons, etc.

What is the difference between CBG and CBD? ｜Explanation based on thesis!

The main difference between CBG and CBD is that CBG produces CBD, but is there a difference in effect?

Learn more about the differences between CBG and CBD here.

American academic paper discovers new effects of CBD and CBG on vomiting!

A 2011 paper published in the American journal Psychopharmacology found that CBD acts as an agonist (activator) by binding to the serotonin receptor 5-HT1A, suppressing nausea and vomiting. rice field.

However, CBG acts as an antagonist (inhibitor) of the serotonin receptor 5-HT1A, and it was found that ingesting CBD first and then CBG inhibited the effect of suppressing vomiting.

American studies have confirmed that CBG and CBD have opposite effects on nausea and vomiting.

So, according to the paper, people experiencing nausea have lower endocannabinoid levels and CB1 receptor expression, so taking CBD may help prevent vomiting.

Reference: psychopharmacology "Effect of cannabigerol on the antiemetic effect of cannabidiol in rats"

American academic paper discovers new effects of CBD and CBG on appetite!

A 2012 study at the University of Reading in England found that CBD administration to fed rats significantly reduced total intake, according to a paper in the US journal Psychopharmacology.

Also, in a 2016 study, when rats were fed CBG, they ate more than twice as much as they normally would.

In other words, research has shown that CBG has an appetite-stimulating effect, while CBD has the opposite effect of suppressing appetite .

Reference: psychopharmacology "Cannabigerol is an appetite stimulant in rats in the satiety state"

psychopharmacology ``Cannabinol and cannabidiol exert opposing effects on rat intake patterns''

What is the effect of CBG? ｜Explain the disadvantages!

CBG is attracting attention for its various effects on the human body, but are there any disadvantages?

I will explain what kind of disadvantages there are in the effect of CBG.

Difficult to obtain due to low production volume

Only about 1% of CBG is available from the cannabis plant.

Cannabigerophyllic acid (CBG-A) contained in cannabis plants changes its structure by the action of enzymes as cannabis matures, and differentiates into cannabinoids such as CBD, CBC, and THC.

Some of the CBG-A that did not change to those cannabinoids changes to CBG by decarboxylation, but most of the CBG-A differentiates into cannabinoids other than CBG, so the amount available is small. is.

By the way, CBD has a content rate of about 20% of the cannabis plant, so you can ask about the low CBG.

Not much research has been done due to its rarity.

CBG has not received much attention due to its rarity and is still under-researched.

Since the content of cannabis can only be less than 1%, it costs a lot to purify a certain amount of CBG.

Therefore, it is true that CBG's efficacy and safety are low because human experiments have not yet been conducted.

However, despite the paucity of research results, CBG holds promise in various fields.

In recent years, in addition to cannabis plants, the development of varieties that can obtain a large amount of CBG is progressing through selective breeding.

What is the effect of CBG? ｜Explain the benefits!

Although CBG is rare and has not been studied much, it is attracting attention for its various effects.

Learn more about the benefits of CBG.

Application to cancer and tumors is being researched

A 2014 study in rats at the University of Naples in Italy found that CBG inhibited the formation of melanoma cells, cancerous pigment cells in the skin.

Therefore, it is being researched with the expectation that it will reduce the progression of cancer and tumors.

If cancer progression can be slowed down, treatment can be continued while prolonging life.

Furthermore, in a mouse study, they found that CBG may reduce inflammatory bowel disease.

The intestine, which has the role of digesting food and absorbing nutrients, is important for humans and must be cared for.

In addition, it is said that 1 in 2 men and 1 in 3 women will develop cancer these days, so CBG may be useful as an effective drug.

Reference: Springerlink "Synthesis and antitumor activity of cannabigerol"

Study done in Spain finds effects on neurodegenerative diseases!

A 2012 study in mice by Spanish researchers found that cannabigerol quinone, a derivative of CBG, reduced symptoms of multiple sclerosis.

Also, in 2015, it was found to suppress motor abnormalities and protect against neuronal degeneration in Huntington's disease mice.

It is said that these effects on neurodegenerative diseases should be investigated as therapeutic agents for neurodegenerative diseases among researchers.

Reference: psychopharmacology “Evidence that cannabigerol is an α2 adrenergic receptor agonist and a 5HT1A receptor antagonist”

American studies are studying the effects on infectious diseases!

The paper ``Uncovering the hidden antibiotic potential of cannabis,'' published on February 4, 2020 at the American Chemical Society, examined the antibacterial effects of 18 cannabinoids against methicillin-resistant Staphylococcus aureus MARS. As a result, research results were announced that CGB has the best antibacterial effect and is equivalent to vancomycin, which is known as a powerful antibiotic.

MARS is resistant to major antibiotics, and if you become infected with MARS, you run the risk of prolonging or becoming more severe.

Therefore, CBG may also be useful in the treatment of bacterial infections as it has antibacterial activity against MARS.

Reference: ACS Publications, “Uncovering the Hidden Antibiotic Potential of Cannabis”

What is the effect of CBG? Explain the difference and effects with CBD! ｜Frequently Asked Questions

Here are some frequently asked questions about the effects of CBG.

Will CBG get high?

CBG has almost no psychoactive effects.

Unlike THC, which contains cannabis components, it is a non-psychoactive cannabinoid, so you can use it without getting high.

Does CBG improve concentration?

Unlike CBD, CBG does not have a concentration-enhancing effect.

However, it is expected to support the work of the ECS (entocannabinoid system), which is related to all bodily functions such as appetite, immune function, and nervous system.

How does it feel when using CBG?

You will not feel any effects when using CBG.

It is said that it takes at least 2 to 5 minutes after ingestion to feel the effect.

In addition, the efficacy and sensation of the effect will change depending on the absorption part of the body and the amount of intake.

There are various methods such as suction, absorption by the stomach and small intestine with edibles, and the experience is different.

What is the effect of CBG? Explain the difference and effects with CBD! ｜Summary

Summary of this article

CBG has almost no known toxicity or side effects.
Only products approved by the Ministry of Health, Labor and Welfare are sold in Japan.
CBG has few experimental events in humans and insufficient evidence for safety and efficacy
CBG is expected in various fields

Currently, CBG is an ingredient that can be taken with confidence because products approved by the Ministry of Health, Labor and Welfare are on the market.

On the other hand, the evidence is still small, so let's expect further research results from now on.

Therefore, we recommend the CBD store "Green", which is licensed by the Ministry of Health, Labor and Welfare and goes to the United States to purchase CBD .

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監修者

株式会社Green　代表取締役荘司晃久
国内初のCBDテイスティング専門店CBD GReEN Storeの社長。元は音響エンジニアリング(PAエンジニア)として活躍。アメリカでCBD製品に出会い、麻という植物の持つポテンシャルを安心・安全に活かすために、国内最大級のCBDをテイスティングできる専門店をオープン。ユーザーのニーズにあったCBD製品を届けることができるように、海外を飛び回ってCBD製品の買い付けをしている。YouTube・Twitter・Instagram・FacebookなどでCBDに関する情報を発信中。

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